Febuary 16, 2001 : The Buffalo Sabres assigned goaltender Martin Biron to the Rochester Americans of the AHL for a one-game conditioning assignment

January 17, 2001 : Dominik Hasek is the winner of the popular vote for the World Team in the 2001 NHL All-Star game

November 7, 2000: The Buffalo Sabres and prospect Martin Biron agreed to terms and was assigned to the Rochester Americans for conditioning. Terms of the contract were not disclosed.

October 6, 2000 : Sabres claimed Petr Skudra from the Boston Bruins on waivers.

October 5, 2000 : Dominik Hasek sustained a knee ligament injury in the Sabres oppener and is expected to miss one week.

June 24, 2000 : Sabres draft Ghyslain Rousseau from the Baie Commeau Drakkar (QMJHL) in the 4th round (111th overall)

June 23, 2000 : Dwayne Roloson selected by the Columbus Blue jackets in the 2000 Expansion Draft